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E954

Saccharin

The oldest artificial sweetener, roughly 300 to 500 times sweeter than sugar.

Sweetener

i Additive Details

| Is E954 Saccharin safe?

Rat studies in the 1970s linked high doses of saccharin to bladder tumours, and products in the United States carried a warning label for two decades. The mechanism was later shown to depend on a urinary protein that rats have and humans do not, so the finding is not considered relevant to people; the US warning requirement was removed in 2000 and saccharin was delisted as a suspected human carcinogen. Saccharin is a sulfonamide derivative and there are occasional reports of skin reactions in people sensitive to sulfonamide drugs, though cross-reactivity is not established.

| Uses

Used in tabletop sweeteners, diet soft drinks, sugar-free chewing gum, reduced-sugar preserves and some medicines. It is stable to heat and acid and has an extremely long shelf life. The E number covers saccharin and its sodium, potassium and calcium salts; sodium saccharin is by far the most common form.

| Interactions

Frequently blended with cyclamate or aspartame, which round out the metallic, bitter aftertaste that saccharin develops at higher concentrations. It is not metabolised — it is absorbed, circulates unchanged and is excreted in the urine — so it supplies no energy and does not raise blood glucose.

| Origin

Synthetic. First made in 1879 from toluene derivatives; modern production uses anthranilic acid or phthalic anhydride routes. There is no natural source.

| Daily Intake

The long-standing ADI is 5 mg per kg of body weight per day, expressed as free imide, set by the EU Scientific Committee on Food and used by JECFA. Saccharin is included in EFSA's ongoing re-evaluation of the authorised sweeteners.

Information is sourced from public regulatory bodies (EFSA, FDA, WHO) and is for reference only. Always read the package and consult a healthcare professional for medical advice.

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